Noninvasive Prenatal Testing Test Versus Chorionic Villus Sampling,Where Are We Now?

作     者：Huijing Zhang Branko Denona 

作者机构：Fetal Medicine UnitRoyal Prince Alfred HospitalSydney 2050Australia. 

出 版 物：《Maternal-Fetal Medicine》 (母胎医学杂志（英文）)

年 卷 期：2024年第6卷第2期

页      面：128-130页

核心收录：

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

主　　题：fetal globally outer 

摘      要：Introduction The discovery of cell-free fetal DNA(cff-DNA),also known as noninvasive prenatal testing(NIPT),by Lo et *** 1997,1 has significantly changed the screening for common chromosomal *** widespread acceptance globally underscores its *** analyzes fetal DNA originating from the apoptosis of the outer cytotrophoblast,the fetal hematopoietic system,and lysis of other fetal *** DNA fraction increases from 10%to 15%between 10 and 20 gestational *** cff-DNA clearance occurs in maternal circulation,spanning from 4 minutes to 2 weeks postpartum.