Driving pressure in mechanical ventilation:A review

作     者：Syeda Farheen Zaidi Asim Shaikh Daniyal Aziz Khan Salim Surani Iqbal Ratnani 

作者机构：Department of MedicineQueen Mary UniversityLondon E14NSUnited Kingdom Department of MedicineAga Khan UniversitySindhKarachi 74500Pakistan Department of MedicineJinnah Postgraduate Medical CenterSindhKarachi 75510Pakistan Department of Medicine and PharmacologyTexas A and M UniversityCollege StationTX 77843United States Department of Anesthesiology and Critical CareHouston Methodist HospitalHoustonTX 77030United States 

出 版 物：《World Journal of Critical Care Medicine》 (世界重症医学杂志)

年 卷 期：2024年第13卷第1期

页      面：15-27页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Driving pressure Acute respiratory distress syndrome Mortality Positive end-expiratory pressure Ventilator induced lung injury Mechanical ventilation 

摘      要：Driving pressure(ΔP)is a core therapeutic component of mechanical ventilation(MV).Varying levels ofΔP have been employed during MV depending on the type of underlying pathology and severity of ***,ΔP levels have also been shown to closely impact hard endpoints such as *** this,conducting an in-depth review ofΔP as a unique,outcome-impacting therapeutic modality is extremely *** is a need to understand the subtleties involved in making sureΔP levels are optimized to enhance outcomes and minimize *** performed this narrative review to further explore the various uses ofΔP,the different parameters that can affect its use,and how outcomes vary in different patient populations at different pressure *** better utilizeΔP in MV-requiring patients,additional large-scale clinical studies are needed.