Successful treatment of Purpureocillium lilacinum pulmonary infection with isavuconazole: A case report
作者机构：Department of Emergency MedicineLishui Central HospitalLishui 323000Zhejiang ProvinceChina Department of HematologyLishui Central HospitalLishui 323000Zhejiang ProvinceChina Department of Clinical LaboratoryThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2024年第12卷第10期
页 面：1772-1777页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Purpureocillium lilacinum Pulmonary infection Isavuconazole Case report
摘 要：BACKGROUND Purpureocillium lilacinum(***)is a saprophytic fungus widespread in soil and *** a causative agent,it is very rarely detected in humans,most commonly in the *** SUMMARY In this article,we reported the case of a 72-year-old patient with chronic lymphocytic leukemia who was admitted with cough and *** tomography revealed an infection in the right lower *** lavage fluid culture and metagenomic next-generation sequencing were ultimately confirmed to have a pulmonary infection with *** was eventually discharged with good outcomes after treatment with *** Pulmonary infection with *** was exceedingly *** currently there are no definitive therapeutic agents,there are reports of high resistance to amphotericin B and fluconazole and good sensitivity to second-generation *** present report is the first known use of isavuconazole for pulmonary *** *** provides new evidence for the characterization and treatment of clinical *** lung infections.
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