Improving patient stratification and selection for curative-intent treatment in localized pancreatic cancer

作     者：Mary P.Martos Haleh Amirian Erin M.Dickey Edmond W.Box Nipun B.Merchant Peter J.Hosein Caitlin A.Hester Jashodeep Datta 

作者机构：Department of SurgeryUniversity of Miami Miller School of MedicineMiamiFLUSA Sylvester Comprehensive Cancer CenterMiamiFLUSA Department of MedicineUniversity of Miami Miller School of MedicineMiamiFLUSA 

出 版 物：《Hepatobiliary Surgery and Nutrition》 (肝胆外科与营养（英文）)

年 卷 期：2024年第13卷第2期

页      面：325-328页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Pancreatic adenocarcinoma pancreatic cancer prognostic model preoperative factors patient stratification 

摘      要：Pancreatic ductal adenocarcinoma(PDAC)is a devastating malignancy,owing in part to the fact that most patients present with advanced disease with only 20%eligible for surgical ***,the dismal oncologic outcomes achieved with surgery alone,coupled with the almost ubiquitous distant recurrence in operable PDAC patients,have mandated a multimodal approach for this *** advent of effective combination chemotherapy regimens delivered increasingly in the perioperative setting,safety and technical mastery of pancreatectomy,and growing appreciation of the molecular underpinnings in PDAC have resulted in gradual but consistent improvements in disease-specific survival and overall survival(OS)in patients with localized PDAC(1).