Development and Validation of Diagnostic Criteria for Elderly Atopic Dermatitis

作     者：Shang-Shang Wang Zheng Li Chao-Ying Gu Hui-Bin Yin Yue-Meng Wu Xu Yao Wei Li Shang-Shang Wang;Zheng Li;Chao-Ying Gu;Hui-Bin Yin;Yue-Meng Wu;Xu Yao;Wei Li

作者机构：Department of DermatologyShanghai Institute of DermatologyHuashan HospitalFudan UniversityShanghai 200040China Department of Allergy and RheumatologyJiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIsHospital for Skin Diseases(Institute of Dermatology)Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China 

出 版 物：《International Journal of Dermatology and Venereology》 (国际皮肤性病学杂志（英文）)

年 卷 期：2024年第7卷第1期

页      面：1-5页

核心收录：

学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

基　　金：supported by the Natural Science Foundation of China(Nos.82003357,82003349,81972939,and 82073446) the National Key R&D Program of China(No.2022YFC3601800) the CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2021-I2M-1-059) the Clinical Research Plan of SHDC(No.SHDC22022302) the Key Project of the Innovation Program of Shanghai Municipal Education Commission(No.2021-01-07-00-07-E00078) the Nanjing Incubation Program for National Clinical Research Centre(No.2019060001) the Key Project of Social Development in Jiangsu Province(No.BE2020632) 

主　　题：atopic dermatitis elderly diagnostic criteria sensitivity clinical features atypical 

摘      要：Objective:Elderly atopic dermatitis(AD)is a newly identified subtype of *** specific diagnostic criteria are needed for elderly AD has been *** study aimed to propose diagnostic criteria for elderly AD and evaluate the ***:A hospital-based study was *** screened the clinical features of 1,312 patients with AD of different ages in 1 cohort and proposed a set of diagnostic criteria for elderly *** criteria were then validated in another cohort of 223 patients clinically diagnosed with elderly AD by dermatologists specialized in AD to examine the diagnostic sensitivity compared with other criteria by chi-square ***:Based on the patients’clinical features,a set of diagnostic criteria for elderly AD were *** new diagnostic criteria showed significantly higher sensitivity than the classical diagnostic criteria(P0.001),especially for mild and moderate AD(P0.001).Of all 223 patients with elderly AD,93.3%fulfilled our criteria,while only 43.5%,65.5%,and 52.0%fulfilled the Hanifin and Rajka criteria,the Japanese Dermatology Academy criteria,and the United Kingdom Working Party criteria,***:The newly proposed criteria for elderly AD yielded high diagnostic sensitivity,particularly for mild and moderate AD.