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Health Care Science

The importance of public engagement in clinical xenotransplantation

作     者:Daniel J.Hurst David K.C.Cooper 

作者机构:Department of Family MedicineRowan-Virtua School of Osteopathic MedicineStratfordNew JerseyUSA Center for Transplantation SciencesMassachusetts General Hospital/Harvard Medical SchoolBostonMassachusettsUSA 

出 版 物:《Health Care Science》 (科学医疗(英文))

年 卷 期:2024年第3卷第2期

页      面:124-130页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:clinical trials ethics public engagement viewpoints xenotransplantation 

摘      要:Over the past several decades,significant scientific progress in xenotransplantation has brought the field to the threshold of clinical *** the past 3 years in the United States,experimental pig kidney and heart xenotransplantation have been performed on human subjects recently declared dead by neurological criteria(decedents).In addition,two pig heart transplants have been carried out in living patients under the United States Food and Drug Administration s expanded access ***,though there has been a flurry of activity there remain unanswered questions regarding how the public views xenotransplantation,what concerns may exist,and how to address these concerns in a meaningful *** paper aims to underscore the importance of public engagement in xenotransplantation,emphasizing the ongoing need for studies to assess public *** current evidence on public engagement studies is reviewed and gaps in our understanding are *** propose practical steps to advance this *** studies to determine the extent of racial/ethnic differences in attitudes to xenotransplantation should be *** and descriptive analysis of certain religious viewpoints—especially minority faiths—would be *** public engagement is an important aspect of public acceptance of novel research that is accompanied by risk,we suggest that xenotransplantation biotechnology companies might consider leading the way in funding this research.

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