Non-alcoholic fatty liver disease and sleep disorders

作     者：Lu-Fang Bu Chong-Yu Xiong Jie-Yi Zhong Yan Xiong Dong-Ming Li Fen-Fang Hong Shu-Long Yang 

作者机构：Department of PhysiologyFuzhou Medical CollegeNanchang UniversityFuzhou 344000Jiangxi ProvinceChina Key Laboratory of Chronic DiseasesFuzhou Medical UniversityFuzhou 344000Jiangxi ProvinceChina Technology Innovation Center of Chronic Disease Research in Fuzhou CityFuzhou Science and Technology BureauFuzhou 344000Jiangxi ProvinceChina Experimental Center of Pathogen BiologyCollege of MedicineNanchang UniversityNanchang 330006Jiangxi ProvinceChina 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2024年第16卷第3期

页      面：304-315页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by National Natural Science Foundation of China,No.82360880,and 82060661 Jiangxi Provincial Natural Science Foundation of China,No.20232ACB206057 Key project of Jiangxi Provincial Department of Education,No.GJJ218104 Teaching reform research project of Jiangxi Province of China,No.JXJG-22-130-1 National Natural Science Foundation of China,No.81660151 Jiangxi Provincial Natural Science Foundation of China,No.20212BAB206092 

主　　题：Non-alcoholic fatty liver disease Sleep duration Sleep quality Sleep disorders Obstructive sleep apnea 

摘      要：Studies have shown that non-alcoholic fatty liver disease(NAFLD)may be associated with sleep *** order to explore the explicit relationship between the two,we systematically reviewed the effects of sleep disorders,especially obstructive sleep apnea(OSA),on the incidence of NAFLD,and analyzed the possible mechanisms after adjusting for confounding *** is independently associated with sleep *** sleep disorders may be the cause of the onset and aggravation of *** excessive or insufficient sleep duration,poor sleep quality,insomnia,sleep-wake disorders,and OSA may increase the incidence of *** that some research suggests a unidirectional causal link between the two,specifically,the onset of NAFLD is identified as a result of changes in sleep characteristics,and the reverse relationship does not hold ***,there is still a lack of specific research elucidating the reasons behind the higher risk of developing sleep disorders in individuals with *** research is needed to establish a clear relationship between NAFLD and sleep *** will lay the groundwork for earlier identification of potential patients,which is crucial for earlier monitoring,diagnosis,effective prevention,and treatment of NAFLD.