Effects of Radix Puerariae, Radix Rehmanniae and Their Compatibility on Blood Glucose and Blood Lipids in Mice

作     者：Yumei ZHANG Yulin ZHAO Yanmei QIN Jialing WEI Xiang QIN Suoyi HUANG 

作者机构：College of Clinical MedicineYoujiang Medical University for NationalitiesBaise 533000China Key Laboratory of Research on Characteristic Ethnic Medicine in the Youjiang River Basin of Guangxi Colleges and UniversitiesBaise 533000China College of PharmacyYoujiang Medical University for NationalitiesBaise 533000China 

出 版 物：《Medicinal Plant》 (药用植物：英文版)

年 卷 期：2024年第15卷第1期

页      面：45-47页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Supported by the National Innovation Planning Project for University Students in 2022 in Guangxi(S202210599012) 

主　　题：Radix Puerariae Radix Rehmanniae Compatibility Hypoglycemic effect Blood lipids 

摘      要：[Objectives]To explore the effects of the compatibility of Radix Puerariae and Radix Rehmanniae on blood glucose and blood lipids in diabetic mouses.[Methods]Diabetic mouse model was *** body weight and fasting blood glucose of mice were measured after 7 and 14 d of administration,and the biochemical indicators of blood lipids(TC,HDL-C,and LDL-C)were detected after 14 d of administration.[Results]Compared with the Radix Puerariae group and Radix Rehmanniae group,the compatibility group(1:2)had the best hypoglycemic effect(P0.05),and TC and LDL-C in the compatibility group(2:1)significantly decreased(P0.05),while HDL-C in the compatibility group(1:1)significantly increased(P0.05).[Conclusions]Radix Puerariae,Radix Rehmanniae and their combination can reduce the blood glucose of diabetic *** compatibility group(1:2)had a significant hypoglycemic effect(P0.05),and LDL-C in the compatibility group(2:1)significantly declined,while HDL-C in the compatibility group(1:1)rose significantly.