Facile Syntheses of New Pyrazolo[1,5-a]pyrimidines Derivatives via Reactions of Enaminones with Aminopyrazole

作     者：LI Ming WANG Shu-wen WEN Li-rong KE Zi-qin 

作者机构：College of Chemistry and Molecular Engineering Qingdao University of Science and Technology Qingdao 266042 P. R. China Department of Chemistry Xinjiang Normal University Urumuqi 830054 P. R. China 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2005年第21卷第6期

页      面：663-667页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：SupportedbytheNationalNaturalScienceFoundationofChina(No.Y2003B01) 

主　　题：Pyrazolo [ 1,5-a ] pyrimidine Enaminone Synthesis Mechanism Crystal structure 

摘      要：Ethyl 7-aryl-2-benzyhhiopyrazolo [ 1,5-a ] pyrimidine-3-carboxylates （3a-3f） were conveniently synthesized through the reactions of enaminones with 5-amino-3-benzyhhio4-ethoxycarbonyl-1 H-pyrazole in good yields and high regioselectivity. The structures of the new compounds were fully characterized by spectroscopic measurmehts, elemental analysis and X-ray diffraction analysis. A plausible reaction mechanism for the formation of the title compounds was also presented.