Immunology reshapes neuroscience,and neuroscience reshapes immunology
作者机构：Department of NeurosurgeryHuashan HospitalInstitute for Translational Brain ResearchState Key Laboratory of Medical NeurobiologyMOE Frontiers Center for Brain ScienceMOE Innovative Center for New Drug Development of Immune Inflammatory DiseasesFudan UniversityShanghai 200040China Department of Laboratory Animal ScienceMOE Frontiers Center for Brain ScienceFudan UniversityShanghai 200032China Neuroscience Research Institute and Department of NeurobiologySchool of Basic Medical SciencesKey Laboratory for NeuroscienceMinistry of Education/National Health Commission and State Key Laboratory of Natural and Biomimetic DrugsPeking UniversityBeijing 100083China PKU-IDG/McGovern Institute for Brain ResearchPeking UniversityBeijing 100871China Faculty of Medicine and Pharmaceutical SciencesZhejiang UniversityHangzhou 310014China School of MedicineTsinghua UniversityBeijing 100084China IDG/McGovern Institute for Brain ResearchCenter for Life SciencesSchool of Life SciencesPeking UniversityBeijing 100871China Chinese Institute for Brain ResearchBeijing 102206China Department of Life SciencesNational Natural Science Foundation of ChinaBeijing 100085China
出 版 物：《Fundamental Research》 (自然科学基础研究（英文版）)
年 卷 期：2024年第4卷第2期
页 面：199-200页
核心收录：
主 题：organs overlap contributing
摘 要：As a result of evolution,our body has evolved into a sophisticated system in which various tissues and organs cooperate in a highly orchestrated manner.Few tissues or organs operate in isolation.The brain serves as the command center of our body and is relatively isolated from the peripheral system due to the presence of the blood-brain barrier(BBB).This barrier prevents direct and extensive interaction between blood cells,plasma molecules,and brain cells,contributing to the longstanding perception of the brain as an“immune-privilegedarea.Consequently,neuroscientists and immunologists historically conducted separate research with minimal overlap between these two disciplines.However,this perspective has undergone reconsideration over the past few decades.
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