Preparation and release of curcumin/silk fibroin/sodium alginate film

作     者：Yerong Yuan Jun’an Zheng Zunchao Liu Wei Li Jiaqing Cao Xiangrong Zhang 

作者机构：Faculty of Functional Food and WineShenyang Pharmaceutical UniversityShenyang 110016China 

出 版 物：《Journal of Polyphenols》 (多酚杂志（英文）)

年 卷 期：2024年第6卷第1期

页      面：1-10页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：funded by Livelihood Plan Project of Department of Science and Technology of Liaoning Province(2021JH2/10300069,2019-ZD-0845) Department of Education of Liaoning Province(LJKZ0918) National College Students’Innovation and Entrepreneurship Training Program(202210163013) 

主　　题：curcumin silk fibroin sodium alginate composite film 

摘      要：The aim of this study was to prepare silk fibroin/sodium alginate composite film containing curcumin by casting *** test was used to optimize the formulation according to the values of tensile strength and elongation at *** release of curcumin in the optimal film was studied in order to explore its application as wound *** results showed that the optimum composition of curcumin/silk fibroin/sodium alginate composite film was as follows:Silk fibroin(70 mg/mL)2.7 g,sodium alginate(24 mg/mL)0.84 g,span 40(5.0 mg/mL)0.4 g,glycerol(3.75%,V/V)3 mL,curcumin(0.2 mg/mL)0.016 *** optimum film showed the tensile strength and the elongation at break was(0.628±0.032)MPa and(0.794±0.046)%,respectively.