The important role of skin biopsies in the diagnosis of mpox

作     者：Wun-Ju Shieh 

作者机构：Department of Microbiology and ImmunologySchool of MedicineTaipei Medical UniversityTaipeiTaiwanChina 

出 版 物：《iLABMED》 (智能检验医学（英文）)

年 卷 期：2023年第1卷第3期

页      面：143-147页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：diagnosis histopathology mpox skin biopsy 

摘      要：Human monkeypox(mpox)is an emerging zoonosis endemic in several Central and West African countries[1].There are two known clades of mpox virus—one that originated in Central Africa(Clade I)and one that originated in West Africa(Clade II).However,cases of mpox have been reported from countries where the disease is not endemic,especially during the 2003 outbreak in the U.S.[2]and the 2022 global outbreak[3,4].The mpox virus in the 2003 *** was transmitted from imported African rodents to domestic North American prairie dogs and subsequently to humans in contact with infected animals[5].No evidence of human‐to‐human transmission was identified,and most of the human cases presented with scattered skin *** transmission route of the 2022 global outbreak,on the contrary,was mainly through intimate human‐to‐human contact,and many cases showed abundant skin lesions with mucosal involvement[6–8].