taBOX: A water-soluble tetraanionic rectangular molecular container for conjugated molecules and taste masking for berberine and palmatine

作     者：Qihan Lin Jiabin Xing Yue-Yang Liu Gang Wu Shi-Jia Liu Hui Wang Wei Zhou Zhan-Ting Li Dan-Wei Zhang Qihan Lin;Jiabin Xing;Yue-Yang Liu;Gang Wu;Shi-Jia Liu;Hui Wang;Wei Zhou;Zhan-Ting Li;Dan-Wei Zhang

作者机构：Department of ChemistryShanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsFudan UniversityShanghai 200438China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2024年第35卷第5期

页      面：175-178页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 10[医学] 

基　　金：the National Natural Science Foundation of China(Nos.22271059 21921003 21890730 and 21890732)for financial support 

主　　题：Macrocycle Multianion Molecular container Molecular recognition Bitter taste masking 

摘      要：A water-soluble macrocycle that bears four carboxylate anions has been designed and prepared,which forms a rectangular cavity that can efficiently encapsulate discrete electron-deficient aromatic compounds,including berberine and *** macrocycle is revealed to be highly biocompatible and able to inhibit the bitter taste of the two drugs.