内侧杏仁核的神经调节素1信号通路调控青春期社会隔离导致的自闭样行为
Medial amygdala NRG1 signaling mediates adolescent social isolation-induced autistic-like behaviors作者机构:Department of PsychiatryInstitute of Brain DiseaseNanfang HospitalSouthern Medical UniversityGuangzhou 510515China Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired IntelligenceSouthern Medical UniversityGuangzhou 510515China
出 版 物:《Science Bulletin》 (科学通报(英文版))
年 卷 期:2024年第69卷第10期
页 面:1375-1379页
核心收录:
学科分类:0710[理学-生物学] 07[理学] 071006[理学-神经生物学]
基 金:supported by the National Natural Science Foundation of China(82071488 and 82271525) the Natural Science Foundation of Guangdong Province(2023A1515010456 and 2021A1515012181)
主 题:社会隔离 impairment prevalence
摘 要:Autistic spectrum disorder(ASD),characterized by impairments in social interaction and repetitive behaviors,is a complex neurodevelopmental brain disorder that is reportedly increasing in prevalence globally[1].It is widely accepted that genetic and environmental factors alone or in combination cause ASD[2].