Tumor deposits in axillary adipose tissue in patients with breast cancer:Do they matter?

作     者：Muhammed Mubarak Rahma Rashid Shaheera Shakeel 

作者机构：Department of HistopathologySindh Institute of Urology and TransplantationKarachi 74200SindhPakistan 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2024年第12卷第6期

页      面：1045-1049页

核心收录：

学科分类：1011[医学-护理学（可授医学、理学学位）] 10[医学] 

主　　题：Breast cancer Tumor deposits Lymph node metastasis Staging 

摘      要：Tumor deposits(TDs)are defined as discrete,irregular clusters of tumor cells lying in the soft tissue adjacent to but separate from the primary tumor,and are usually found in the lymphatic drainage area of the primary *** definition,no residual lymph node structure should be identified in these tumor *** present,TDs are mainly reported in colorectal cancer,with a few reports in gastric *** are very few reports on breast cancer(BC).For TDs,current dominant theories suggest that these are the result of lymph node metastasis of the tumor with complete destruction of the lymph nodes by the tumor *** some pathologists classify a TD as two lymph node metastases for *** pathologists also believe that TDs belong to the category of disseminated ***,regardless of the origin,TDs are an indicator of poor ***,for BC,sentinel lymph node biopsy is generally used at *** radical axillary lymph node dissection should be adopted for BC with TDs in axillary lymph nodes is still *** present commentary of this clinical issue has certain guiding *** is aimed to increase the awareness of the scientific community towards this under-recognized problem in BC pathology.