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Light-controlled soft bio-microrobot

作     者:Jianyun Xiong Xing Li Ziyi He Yang Shi Ting Pan Guoshuai Zhu Dengyun Lu Hongbao Xin Jianyun Xiong;Xing Li;Ziyi He;Yang Shi;Ting Pan;Guoshuai Zhu;Dengyun Lu;Hongbao Xin

作者机构:Guangdong Provincial Key Laboratory of Nanophotonic ManipulationInstitute of NanophotonicsJinan University511443 GuangzhouChina 

出 版 物:《Light(Science & Applications)》 (光(科学与应用)(英文版))

年 卷 期:2024年第13卷第3期

页      面:531-543页

核心收录:

学科分类:07[理学] 0701[理学-数学] 070101[理学-基础数学] 

基  金:supported by the National Natural Science Foundation of China(12374286,12204196,and 32271405) the National Key Research and Development Program of China(2023YFF0613700) Guangdong Basic and Applied Basic Research Foundation(2022B1515120012) Science and Technology Program of Guangzhou(202201010370) 

主  题:narrow illumination curved 

摘      要:Micro/nanorobots hold exciting prospects for biomedical and even clinical applications due to their small size and high ***,it is still a big challenge to maneuver micro/nanorobots into narrow spaces with high deformability and adaptability to perform complicated biomedical ***,we report a light-controlled soft bio-microrobots(called“Ebot)based on Euglena gracilis that are capable of performing multiple tasks in narrow microenvironments including intestinal mucosa with high controllability,deformability and *** motion of the Ebot can be precisely navigated via light-controlled polygonal flagellum ***,the Ebot shows highly controlled deformability with different light illumination duration,which allows it to pass through narrow and curved microchannels with high *** these features,Ebots are able to execute multiple tasks,such as targeted drug delivery,selective removal of diseased cells in intestinal mucosa,as well as photodynamic *** light-controlled Ebot provides a new bio-microrobotic tool,with many new possibilities for biomedical task execution in narrow and complicated spaces where conventional tools are difficult to access due to the lack of deformability and bio-adaptability.

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