A proton birdcage coil integrated with interchangeable single loops for multi-nuclear MRI/MRS

作     者：Yi ZHANG Zhiyan QUAN Feiyang LOU Yujiao FANG Garth J.THOMPSON Gao CHEN Xiaotong ZHANG Yi ZHANG;Zhiyan QUAN;Feiyang LOU;Yujiao FANG;Garth J.THOMPSON;Gao CHEN;Xiaotong ZHANG

作者机构：Department of Neurosurgerythe Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310009China Key Laboratory of Precise Treatment and Clinical Translational Research of Neurological DiseasesHangzhou310009China MOE Frontier Science Center for Brain Science and Brain-machine IntegrationZhejiang UniversityHangzhou310058China Interdisciplinary Institute of Neuroscience and TechnologyCollege of Biomedical Engineering&Instrument ScienceZhejiang UniversityHangzhou310027China School of MedicineZhejiang UniversityHangzhou310020China iHuman InstituteSchool of Life Science and TechnologyShanghaiTech UniversityShanghai201210China College of Electrical EngineeringZhejiang UniversityHangzhou310027China 

出 版 物：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 (浙江大学学报（英文版）B辑（生物医学与生物技术）)

年 卷 期：2024年第25卷第2期

页      面：168-180页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 09[农学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：This work was supported in part by the STI 2030-Major Projects(No.2021ZD0200401) the National Key Research and Development Program of China(No.2018YFA0701400) the National Natural Science Foundation of China(Nos.52277232,52293424,81701774,and 61771423) the Fundamental Research Funds for the Central Universities(Nos.226-2022-00136 and 226-2023-00125) the Zhejiang Provincial Natural Science Foundation of China(No.LR23E070001),the Key R&D Program of Jiangsu Province(No.BE2022049) the Key-Area R&D Program of Guangdong Province(No.2018B030333001),China 

主　　题：Energy metabolism Magnetic resonance imaging(MRI) Magnetic resonance spectroscopy(MRS) Multi-nuclear Radiofrequency coil Three-dimensional(3D)printing 

摘      要：Energy metabolism is fundamental for *** encompasses the utilization of carbohydrates,lipids,and proteins for internal processes,while aberrant energy metabolism is implicated in many *** the present study,using three-dimensional(3D)printing from polycarbonate via fused deposition modeling,we propose a multi-nuclear radiofrequency(RF)coil design with integrated 1H birdcage and interchangeable X-nuclei(^(2)H,^(13)C,^(23)Na,and^(31)P)single-loop coils for magnetic resonance imaging(MRI)/magnetic resonance spectroscopy(MRS).The single-loop coil for each nucleus attaches to an arc bracket that slides unrestrictedly along the birdcage coil inner surface,enabling convenient switching among various nuclei and animal *** to a commercial 1H birdcage coil,the proposed 1H birdcage coil exhibited superior signal-excitation homogeneity and imaging signal-to-noise ratio(SNR).For X-nuclei study,prominent peaks in spectroscopy for phantom solutions showed excellent SNR,and the static and dynamic peaks of in vivo spectroscopy validated the efficacy of the coil design in structural imaging and energy metabolism detection simultaneously.