Leukocyte immunoglobulin-like receptor B2:A promising biomarker for colorectal cancer
作者机构：Department of GastroenterologyThe Affiliated Huai'an No.1 People's Hospital of Nanjing Medical UniversityHuai'an 223300Jiangsu ProvinceChina
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2024年第30卷第4期
页 面：421-423页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Colorectal cancer Leukocyte immunoglobulin-like receptor B2 Angiopoietinlike protein 2 Therapeutic target Noninvasive screening biomarker
摘 要：According to the latest global cancer statistics,colorectal cancer(CRC)has emerged as the third most prevalent malignant tumor across the *** recent decades,the medical field has implemented several levels of CRC screening tests,encompassing fecal tests,endoscopic examinations,radiological examinations and blood *** studies have shown that leukocyte immunoglobulin-like receptor B2(LILRB2)is involved in inhibiting immune cell function,immune evasion,and promoting tumor progression in acute myeloid leukemia and nonsmall cell lung ***,its interaction with CRC has not been reported ***,a study published in the World Journal of Gastroenterology revealed that LILRB2 and its ligand,angiopoietin-like protein 2,are markedly overexpressed in *** overexpression is closely linked to tumor progression and is indicative of a poor *** study highlights the potential of utilizing the concentration of LILRB2 in serum as a promising biomarker for ***,there is still room for discussion regarding the data processing and analysis in this research.
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