Comprehensive effects of traditional Chinese medicine treatment on heart failure and changes in B-type natriuretic peptide levels: A meta-analysis

作     者：Li-Li Xia Shu-Yun Yang Jun-Yao Xu Han-Qing Chen Zhu-Yuan Fang 

作者机构：Hypertension Research InstituteAffiliated Hospital of Nanjing University of Chinese MedicineNanjing 210004Jiangsu ProvinceChina Department of General PracticeSoutheast University Affiliated Zhongda HospitalNanjing 210009Jiangsu ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2024年第12卷第4期

页      面：766-776页

核心收录：

学科分类：100506[医学-中医内科学] 1006[医学-中西医结合] 1005[医学-中医学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：Traditional Chinese medicine Heart failure Comprehensive clinical outcomes Traditional Chinese medicine syndrome score B-type natriuretic peptide level Meta-analysis©The Author(s)2024.Published by Baishideng Publishing Group Inc. 

摘      要：BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and *** traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are *** study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF *** encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established *** results offer crucial insights into the potential advantages and constraints of TCM in HF *** on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and *** quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 ***,the quality of evidence was rated according to the GRADE *** A total of 1098 RCTs were initially *** screening,16 RCTs were finally included in our study,which were published between 2020 and *** RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 *** syndrome differentiation was analyzed in 11 of the included *** all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP *** meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0