Identification of novel biomarkers for varicocele using iTRAQ LC-MS/MS technology

作     者：Xianfeng Lu Na Li Lufang Li Yongai Wu Xuefeng Lyu Yingli Cao Jianrong Liu Qin Qin 

作者机构：Department of PediatricsShanxi Provincial People’s HospitalTaiyuanShanxi 030012China Department of Reproductive GeneticsHeping Hospital Affiliated to Changzhi Medical CollegeChangzhiShanxi 046099China Department of BiochemistryBasic Medicine CollegeShanxi Medical UniversityTaiyuanShanxi 030607China Reproductive Medical DepartmentShanxi Provincial People’s HospitalTaiyuanShanxi 030012China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2024年第137卷第3期

页      面：371-372页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by grants from the National Natural Science Foundation of China(Nos.81401192 and 81973864) Fundamental Research Program of Shanxi Province(No.20210302123348) Four"Batches"Innovation Project of Invigorating Medical through Science and Technology of Shanxi Province(No.2022XM25) 

主　　题：prevention incidence exact 

摘      要：To the Editor:Varicocele(VC)is a vascular disease and considered as the main cause of male infertility.^([1])The incidence of VC in the common male population was 4.4–22.6%,of which the incidence of primary infertility was 35–40%,while the incidence of secondary infertility was as high as 80%.^([2])The exact pathophysiological mechanism of male infertility caused by VC and regulative molecules are still *** and definite molecular markers of VC disease are helpful for early prevention and timely *** study aimed to screen candidate regulative molecules playing a role in male infertility caused by VC.