Engineering of ovarian tissue for ovarian dysfunctions:A review
作者机构：Department of Evidence-Based Medicine and Scientific ManagementWest Kazakhstan Marat Ospanov Medical UniversityAktobeKazakhstan Department of Surgery and Urology No.2West Kazakhstan Medical UniversityAktobeKazakhstan Department of Surgery and TransplantationAktobe Medical CenterAktobeKazakhstan Department of Internal DiseasesWest Kazakhstan Marat Ospanov Medical UniversityAktobeKazakhstan Stem Cell Research CenterTabriz University of Medical SciencesTabrizIran Department of Reproductive BiologyFaculty of Advanced Medical SciencesTabriz University of Medical SciencesTabrizIran Department for Scientific WorkWest-Kazakhstan Marat Ospanov Medical UniversityAktobeKazakhstan
出 版 物：《Asian pacific Journal of Reproduction》 (亚太生殖杂志（英文版）)
年 卷 期：2024年第13卷第1期
页 面：3-11页
学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学]
主 题：Female gonads Tissue engineering Estrogen Reproductive system
摘 要：This review explores tissue engineering as a potential solution for reproductive health issues in women caused by genetic or acquired diseases,such as premature ovarian failure or *** loss of ovarian function can lead to infertility,osteoporosis,and cardiovascular *** replacement therapy is a common treatment,but it has limitations and *** review focuses on two main approaches in tissue engineering:scaffold-based(3D printing,electrospinning,decellularization)and scaffold-free(stem cell transplantation,organoid cultivation).Both approaches show promise in preclinical studies for creating functional ovarian *** include vascularization,innervation,long-term function,and *** these challenges,tissue engineering offers a potential avenue for restoring fertility and hormone balance in women with ovarian dysfunction.
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