Predictive value of Hajibandeh index in determining peritoneal contamination in acute abdomen:A cohort study and meta-analysis

作     者：Shahab Hajibandeh Shahin Hajibandeh Louis Evans Bethany Miller Jennifer Waterman Suhaib JS Ahmad Jay Hale Adnan Higgi Bethan Johnson Dafydd Pearce Ahmed Hazem Helmy Nader Naguib Andrew Maw 

作者机构：Department of General SurgeryUniversity Hospital of WalesCardiff CF144XWUnited Kingdom Department of General SurgeryRoyal Stoke University HospitalStoke-on-Trent ST46QGUnited Kingdom Department of General SurgeryYsbyty GwyneddBangor LL572PWUnited Kingdom Department of General SurgeryRoyal Glamorgan HospitalPontyclun CF728XRUnited Kingdom Department of General SurgeryGlan Clwyd HospitalRhyl LL185UJUnited Kingdom 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2023年第15卷第12期

页      面：2747-2756页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Hajibandeh index Laparotomy Mortality Peritonitis Contamination 

摘      要：BACKGROUND Hajibandeh index(HI),derived from combined levels of C-reactive protein,lactate,neutrophils,lymphocytes and albumin,is a modern predictor of peritoneal contamination and mortality in patients with acute abdominal *** To validate the performance of HI in predicting the presence and nature of peritoneal contamination in patients with acute abdominal pathology in a larger cohort study and to synthesis evidence in a systematic review and *** The STROBE guidelines and the PRISMA statement standards were followed to conduct a cohort study(ChiCTR2200056183)and a meta-analysis(CRD420-22306018),*** adult patients undergoing emergency laparotomy for acute abdominal pathology were *** accuracy of the HI was evaluated using receiver operating characteristic(ROC)curve analysis in the cohort study and using weighted summary area under the curve(AUC)under the fixed and random effects modelling in the *** Quality Assessment of Diagnostic Accuracy Studies 2 criteria were used for methodological quality assessment of the included *** A total of 1437 patients were included(700 from the cohort study and 737 from the literature search).ROC curve analysis of the cohort study showed that the AUC of HI for presence of contamination,purulent contamination and feculent contamination were 0.79[95%confidence interval(CI):0.76-0.82,P0.0001],0.76(95%CI:0.72-0.80,P0.0001),and 0.83(95%CI:0.79-0.86,P0.0001),*** meta-analysis showed that the pooled AUC of HI for presence of contamination,purulent contamination and feculent contamination were 0.79(95%CI:0.75-0.83),0.78(95%CI:0.74-0.81),and 0.80(95%CI:0.77-0.83),*** The HI is a strong and accurate predictor of intraperitoneal *** the available evidence is robust,it is limited to the studies conducted by our evidence synthesis *** encourage other researchers to validate performance of HI in predicting the pr