Actin(g) toward a revised understanding of the role of cytoskeletal dynamics in neuronal bioenergetics

作     者：Sabrina M.Holland Gianluca Gallo Sabrina M.Holland;Gianluca Gallo

作者机构：Department of Neural SciencesShriners Pediatric Research CenterLewis Katz School of Medicine at Temple UniversityPhiladelphiaPAUSA 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2024年第19卷第10期

页      面：2109-2110页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学] 

基　　金：supported by National Institute of Health awards NS118000 and NS128049 (to GG) 

主　　题：metabolism homeostasis degeneration 

摘      要：Neurons are energy-demanding *** in energy metabolism can quickly interrupt neuronal function,leading to cell death and *** instance,ischemia rapidly depletes adenosine triphosphate(ATP)thereby disrupting energy-dependent cellular processes crucial for homeostasis,and axon degeneration is preceded by a collapse of axonal ATP levels.