Genetic Polymorphism of 38 Y-chromosome Short Tandem Repeats in Beijing Han Population from China
作者机构：Shanghai Key Lab of Forensic MedicineKey Lab of Forensic ScienceMinistry of JusticeAcademy of Forensic ScienceShanghaiChina Key Laboratory of Evidence Science of Ministry of EducationChina University of Political Science and LawBeijingChina Beijing Tianping Judicial Expert CenterBeijingChina
出 版 物：《Journal of Forensic Science and Medicine》 (法庭科学与法医学杂志（英文）)
年 卷 期：2023年第9卷第4期
页 面：340-346页
学科分类：0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 08[工学] 09[农学] 0838[工学-公安技术] 071007[理学-遗传学] 0901[农学-作物学] 100105[医学-法医学] 090102[农学-作物遗传育种] 10[医学]
基 金：supported by opening research grants from Shanghai Key Lab of Forensic Medicine,Key Lab of Forensic Science,Ministry of Justice,PR.China(Academy of Forensic Science)(No.KF202111) supported by the Fundamental Research Funds for the Central Universities
主 题：Genetic distance genetic polymorphism Han nationality in Beijing short tandem repeats Y-chromosome
摘 要：Objective:To investigate 38 Y-chromosome short tandem repeat(Y-STR)genetic polymorphisms in Beijing Han and analyze the genetic distance with neighboring or linguistically similar *** and Methods:In the study,we selected 531 unrelated male individuals of Beijing Han,and the results were statistically analyzed by testing with GSTAR™41Y ***:The allele peak heights were balanced among the Y loci,the amplified fragment ranged from 100 to 500 bps.A total of 531 haplotypes were detected in 531 *** null genotypes were observed on locus *** and three double alleles were observed on single-copy locus DYS576 and DYS19,***385 a/b,DYF387S1 a/b,and DYS527 a/b were more common in double copies,but 3,13,and 11 triple alleles were detected,*** gene diversity values of Y-STRs except DYS391,DYS438,and DYS645 were***-seven Y-STRs of Beijing Han population were selected for genetic distance comparison with 17 populations including Changchun Han,with Rst values ranging from 0.0002 to ***:The 38 Y-STRs in this study have strong male lineage identification ability and have great potential for individual identification,kinship identification,Y-STR database construction,and genetic relationship research.
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