Effect of ultrasound-guided lumbar square muscle block on stress response in patients undergoing radical gastric cancer surgery
作者机构:Department of UltrasoundAffiliated Hospital of Jiangnan UniversityWuxi 214122Jiangsu ProvinceChina
出 版 物:《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志(英文版)(电子版))
年 卷 期:2023年第15卷第12期
页 面:2093-2100页
核心收录:
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Ultrasound-guided quadratus lumborum block Radical gastric cancer surgery Stress response Intestinal barrier function Postoperative analgesia Rehabilitation
摘 要:BACKGROUND Radical surgery is a common treatment for patients with gastric cancer;however,it can lead to postoperative complications and intestinal barrier ***-guided quadratus lumborum block is often used for postoperative analgesia,but its effects on stress response and intestinal barrier function are not well *** To investigate the effects of an ultrasound-guided quadratus lumborum block on stress response and intestinal barrier function in patients undergoing radical surgery for gastric *** A total of 100 patients undergoing radical surgery for gastric cancer were randomly categorized into observation and control *** adrenaline and cortisol levels,intestinal mucosal barrier indexes,and complication rates were compared between the two groups before,during,and 1 day after *** The observation group had significantly lower plasma adrenaline and cortisol levels during surgery and at 1 day postoperatively than that of the control group(P0.05).Additionally,intestinal barrier indexes(endotoxin and D-dimer)at 1 day postoperatively were significantly lower in the observation group than in the control group(P0.05).CONCLUSION Ultrasound-guided quadratus lumborum block could reduce stress response,protect intestinal barrier function,and decrease the incidence of complications in patients undergoing radical surgery for gastric *** technique has the potential for clinical applications.