The efficacy of full-thickness endoscopic resection of subepithelial tumors in the gastric cardia
作者机构：Endoscopy CenterZhongshan Hospital Fudan UniversityShanghai 200032China
出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志（英文版）（电子版）)
年 卷 期：2023年第15卷第12期
页 面：2111-2119页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by National Natural Science Foundation of China,No.82273025 China Postdoctoral Science Foundation,No.2022TQ0070 and No.2022M710759 Shanghai Municipal Commission of Science and Technology,No.22JC1403003 and No.22S31903800
主 题：Endoscopic full-thickness resection Submucosal tunneling endoscopic resection Gastrointestinal stromal tumor Gastric cardia Gastric subepithelial tumors
摘 要：BACKGROUND Gastric subepithelial tumors(SETs)may harbor potential *** it is well recognized that large SETs should be resected,the precise treatment strategy remains *** to surgical resection,endoscopic resection(ER)has many advantages;however,ER of SETs in the cardia is *** To evaluate the safety and efficacy of endoscopic full-thickness resection(EFTR)for the treatment of gastric cardia *** We retrospectively reviewed data from all patients with SETs originating from the muscularis propria layer in the gastric cardia that were treated by EFTR or submucosal tunneling ER(STER)at Zhongshan Hospital Fudan University between November 2014 and May *** characteristics and clinical outcomes,including procedure times and complications rates,were compared between groups of patients receiving EFTR and *** A total of 171 tumors were successfully removed[71(41.5%)tumors in the EFTR and 100(58.5%)tumors in the STER group].Gastrointestinal stromal tumors(GISTs)were the most common *** en bloc resection rate was 100%in the EFTR group vs 97.0%in STER group(P0.05).Overall,the EFTR group had a higher complete resection rate than the STER group(98.6%vs 91.0%,P0.05).The procedure time was also shorter in the EFTR group(44.63±28.66 min vs 53.36±27.34,P0.05).The most common major complication in both groups was electrocoagulation *** was no significant difference in total complications between the two groups(21.1%vs 22.0%,P=0.89).CONCLUSION EFTR of gastric cardia SETs is a very promising method to facilitate complete resection with similar complications and reduced operative times compared to *** cases of suspected GISTs or an unclear diagnosis,EFTR should be recommended to ensure complete resection.
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