Value of Chuanjin Qinggan decoction in improving the depressive state of patients with herpes zoster combined with depression
作者机构：Department of DermatologyYantai Hospital of Traditional Chinese MedicineYantai 264000Shandong ProvinceChina Department of GeriatricsYantai Traditional Chinese Medicine HospitalYantai 264000Shandong ProvinceChina
出 版 物：《World Journal of Psychiatry》 (世界精神病学杂志)
年 卷 期：2023年第13卷第12期
页 面：1037-1045页
核心收录：
基 金：This study was reviewed and approved by Yantai Hospital of Traditional Chinese Medicine
主 题：Chuanjin Qinggan decoction Selective 5-hydroxytryptamine reuptake inhibitor Herpes zoster Depression Sleep quality Adverse reaction
摘 要：BACKGROUND Western medicine is beneficial for the recovery of neurological function in patients with depression,but some patients experience side effects such as headaches,dizziness,nausea,gastrointestinal symptoms,insomnia,and cardiac *** recent years,integrative medicine has achieved positive results in the treatment of various *** To study Chuanjin Qinggan decoction combined with selective serotonin reuptake inhibitors(SSRIs)in patients with herpes zoster complicated by *** Patients with herpes zoster complicated by depression who were treated at the Yantai Hospital of Traditional Chinese Medicine from January 2021 to December 2022 were retrospectively selected as research *** them,43 patients with herpes zoster complicated by depression who received SSRI treatment between January and December 2021 were assigned to the Western medicine group,while those who received combined treatment of traditional Chinese and Western medicine between January and December 2022 were assigned to the combined *** groups were treated for eight *** degree of pain,effect of herpes zoster treatment,degree of improvement in depressive symptoms,serum neurotransmitter levels,sleep quality,and occurrence of adverse reactions were compared between the two *** We found that after eight weeks of drug treatment,the two treatment schemes achieved differing *** further comparison,we found that,compared with patients treated with SSRIs alone,patients treated with Chuanjin Qinggan decoction combined with SSRIs showed more significant improvement in depression and a greater increase in dopamine and 5-hydroxytryptamine levels after treatment(P0.05).Patients treated with Chuanjin Qinggan decoction combined with SSRIs also experienced lower pain,better treatment efficacy for herpes zoster,better sleep quality,and a lower incidence of adverse reactions compared to those treated with SSRIs alone(P0.05).All minor adverse
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