Glycolysis and acute lung injury:A review

作     者：Yang Yi Jun Chen Nan Li Yue Huang Jichao Peng Xiaoran Liu Yang Yi;Jun Chen;Nan Li;Yue Huang;Jichao Peng;Xiaoran Liu

作者机构：College of Emergency TraumaHainan Medical UniversityHaikouChina Key Laboratory of Hainan Trauma and Disaster Rescuethe First Affiliated Hospital of Hainan Medical UniversityHaikouChina Key Laboratory of Emergency and Trauma Ministry of EducationHainan Medical UniversityHaikouChina Danzhou People’s HospitalDanzhouChina 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2023年第16卷第11期

页      面：490-497页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by National Natural Science Foundation of China(No.81960351) High-level Talent Fund of Hainan Province(No.822RC835) 

主　　题：Acute lung injury Glycolysis Hypoxia-inducible factor 1 Endothelium Macrophages 

摘      要：Acute lung injury is featured as diffuse pulmonary edema and persistent hypoxemia caused by lung or systemic *** is believed that these pathological changes are associated with damage to the alveolar epithelium and vascular endothelium,recruitment of inflammatory cells,and inflammatory factor *** recent years,the metabolic reprogramming of lung parenchymal cells and immune cells,particularly alterations in glycolysis,has been found to occur in acute lung *** of glycolysis can reduce the severity of acute lung ***,this review focuses on the interconnection between acute lung injury and glycolysis and the mechanisms of interaction,which may bring hope for the treatment of acute lung injury.