The effect of kiwi berry(Actinidia arguta)on preventing and alleviating loperamide-induced constipation

作     者：Jiyue Zhang Dongnan Li Qilin Tian Yumeng Ding Hanqian Jiang Guang Xin Shunchang Cheng Siyi Tang Chenyu Jin Jinlong Tian Bin Li 

作者机构：College of Food ScienceShenyang Agricultural UniversityShenyang 110866LiaoningChina 

出 版 物：《Food Innovation and Advances》 (食品创新与进展（英文）)

年 卷 期：2023年第2卷第1期

页      面：1-8页

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 08[工学] 083203[工学-农产品加工及贮藏工程] 

基　　金：The First Batch of Liaoning'Unveiling Leader'Scientific and Technological Projects(2021JH1/10400036) China Agriculture Research System of MOF and MARA(CARS-29) Liaoning Province food processing chief science and technology special commissioner(2022JH5/10400125) 

主　　题：constipation prevention colon 

摘      要：This research aimed to study the preventive and relieving outcomes of kiwi berry on *** administration of kiwi berries to mice resulted in a significant increase in body weight gain of 148.2%compared to mice that were *** number of stools and the water content of stools both increased by 138.5%and 106.5%,*** gastrointestinal transit rate increased by 45.3%,and the time it took for the first dark stool to form decreased by 57.5%.The levels of the excitability neurotransmitters were found to be higher in the group that had been given kiwi berries in comparison to the group that had been given *** opposite results were produced by vasoactive intestinal peptide(VIP)and aquaporin-3(AQP3).In addition,kiwi berry consumption may lessen epithelial cell apoptosis and promote colon *** the results point to kiwi berries as an extremely promising food supplement for the prevention and relief of constipation in the future since they successfully prevent and alleviate constipation brought on by loperamide.