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Tripartite motif-containing protein 11(TRIM11):a novel weapon against Alzheimer’s disease

作     者:Yichu Fu Bi Zhang Jianfeng Liu Yichu Fu;Bi Zhang;Jianfeng Liu

作者机构:College of Life Science and TechnologyKey Laboratory of Molecular Biophysics of MOEHuazhong University of Science and TechnologyWuhanHubei 430074China 

出 版 物:《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗(英文))

年 卷 期:2024年第9卷第2期

页      面:339-340页

核心收录:

学科分类:0710[理学-生物学] 1002[医学-临床医学] 100203[医学-老年医学] 10[医学] 

基  金:support from the National Key Research and Development Program of China(2022YFA1302901 to B.Z.) the National Natural Science Foundation of China(32271210 to B.Z.) 

主  题:Alzheimer tau TRIM 

摘      要:In a recent study published in Science,Zhang et *** that tripartite motif-containing(TRIM)protein 11(TRIM11)exhibited strong inhibition on tau aggregation,which is a pathological characteristic of tauopathies including Alzheimer’s disease(AD).1 This makes TRIM11 a promising novel target for the treatment of AD and other tauopathies.

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