Tripartite motif-containing protein 11(TRIM11):a novel weapon against Alzheimer’s disease
作者机构:College of Life Science and TechnologyKey Laboratory of Molecular Biophysics of MOEHuazhong University of Science and TechnologyWuhanHubei 430074China
出 版 物:《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗(英文))
年 卷 期:2024年第9卷第2期
页 面:339-340页
核心收录:
学科分类:0710[理学-生物学] 1002[医学-临床医学] 100203[医学-老年医学] 10[医学]
基 金:support from the National Key Research and Development Program of China(2022YFA1302901 to B.Z.) the National Natural Science Foundation of China(32271210 to B.Z.)
摘 要:In a recent study published in Science,Zhang et *** that tripartite motif-containing(TRIM)protein 11(TRIM11)exhibited strong inhibition on tau aggregation,which is a pathological characteristic of tauopathies including Alzheimer’s disease(AD).1 This makes TRIM11 a promising novel target for the treatment of AD and other tauopathies.