Liquid-liquid phase separation as a major mechanism of plant abiotic stress sensing and responses
作者机构：Shanghai Center for Plant Stress BiologyCAS Center for Excellence in Molecular Plant SciencesChinese Academy of SciencesShanghaiChina Institute of Advanced Biotechnology and School of Life SciencesSouthern University of Science and TechnologyShenzhenChina Center for Advanced Bioindustry TechnologiesChinese Academy of Agricultural SciencesBeijingChina
出 版 物：《Stress Biology》 (逆境生物学（英文）)
年 卷 期：2023年第3卷第1期
页 面：610-620页
学科分类：09[农学] 0903[农学-农业资源与环境]
基 金：supported by the National Natural Science Foundation of China(Grant No.32270283 and 32070295) the Science and Technology Commission of Shanghai Municipality(Grant no.22ZR1469600)
主 题：Liquid-liquid phase separation Biomolecular condensates Stress sensors Osmotic stress High temperature
摘 要：Identification of environmental stress sensors is one of the most important research topics in plant abiotic stress *** strategies to identify stress sensors or early signaling components based on the cell membrane as a primary site of sensing and calcium signal as a second messenger have had only limited ***,the current theoretical framework underlying stress sensing in plants should be reconsidered and additional mechanisms need to be ***,accumulating evidence has emerged to suggest that liquid-liquid phase separation(LLPS)is a major mechanism for environmental stress sensing and response in *** this review,we briefly introduce LLPS regarding its concept,compositions,and dynamics,and then summarize recent progress of LLPS research in plants,emphasizing the contribution of LLPS to the sensing of various environmental stresses,such as dehydration,osmotic stress,and low and high ***,we propose strategies to identify key proteins that sense and respond to environmental stimuli on the basis of LLPS,and discuss the research directions of LLPS in plant abiotic stress responses and its potential application in enhancing stress tolerance in crops.
维普期刊数据库