Printed Biosensors for the Detection of Alzheimer’s Disease Based on Blood Biomarkers

作     者：Yu Zeng Zhen Huang Yibiao Liu Tailin Xu Yu Zeng;Zhen Huang;Yibiao Liu;Tailin Xu

作者机构：Longgang Central Hospital of ShenzhenShenzhen518116China School of Biomedical EngineeringShenzhen UniversityShenzhen518060China 

出 版 物：《Journal of Analysis and Testing》 (分析检测（英文）)

年 卷 期：2024年第8卷第2期

页      面：133-142页

核心收录：

学科分类：1002[医学-临床医学] 080202[工学-机械电子工程] 08[工学] 100203[医学-老年医学] 0802[工学-机械工程] 10[医学] 

基　　金：funded by the Shenzhen Science and Technology Innovation Committee(JCYJ20220530153811027) 

主　　题：Printed biosensors Alzheimer’s disease Blood biomarkers Printing technology 

摘      要：Alzheimer’s disease(AD)is a chronic neurodegenerative disorder,and early diagnosis plays a crucial role in its prevention and *** recent years,blood-based biomarkers for early AD diagnosis have gained attention due to their non-invasiveness and minimal adverse reactions,which make them an attractive *** the onset of the COVID-19 pandemic,visiting large medical examination centers for blood tests has become increasingly *** trend is shifting towards community or home-based sampling,which relies on the development and application of portable,miniaturized,and highly sensitive *** the various sensors used for detecting blood biomarkers in AD,printed sensors demonstrate great potential in AD blood biomarker detection due to their ease of miniaturization,scalability for mass production,and compatibility with various detection *** this review,we focus on discussing the application of printed sensors in the analysis of blood biomarkers for *** also explore the challenges faced by printed sensors in early diagnosis based on AD blood biomarkers and propose potential solutions to address these challenges.