Fabrication of micro-nano patterned materials mimicking the topological structure of extracellular matrix for biomedical applications
作者机构:CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China School of Future TechnologyUniversity of Chinese Academy of SciencesBeijing 100049China
出 版 物:《Nano Research》 (纳米研究(英文版))
年 卷 期:2024年第17卷第5期
页 面:4244-4258页
核心收录:
学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 08[工学] 0805[工学-材料科学与工程(可授工学、理学学位)] 0703[理学-化学] 0836[工学-生物工程] 0702[理学-物理学]
基 金:supported by Key Research Program of Frontier Sciences of CAS(No.QYKJZD-SSW-SLH02)
主 题:micro/nano hybrid materials patterning fabrication techniques extracellular matrix substrate-cell interaction biomedical engineering
摘 要:With the advent of tissue engineering and biomedicine,the creation of extracellular matrix(ECM)biomaterials for in vitro applications has become a prominent and promising *** ECM materials provide physical,biochemical,and mechanical properties that guide cellular behaviors,such as proliferation,differentiation,migration,and *** micro-and nano-patterned materials have a unique surface topology and low energy replication process that directly affect cellular biological behaviors at the interface,the fabrication of micro-nano pattern biomaterials and the regulation of surface physical and chemical properties are of great significance in the fields of cell regulation,tissue engineering,and regenerative ***,we provide a comprehensive review of the progress in the fabrication and application of patterned materials based on the coupling of mechanical action at the micro-and nano-meter scale,including photolithography,micro-contact printing,electron beam lithography,electrospinning,and 3D printing ***,a summary of the fabrication process,underlying principles,as well as the advantages and disadvantages of various technologies are *** also discuss the influence of material properties on the fabrication of micro-and nano-patterns.