Fabrication of micro-nano patterned materials mimicking the topological structure of extracellular matrix for biomedical applications
作者机构：CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China School of Future TechnologyUniversity of Chinese Academy of SciencesBeijing 100049China
出 版 物：《Nano Research》 (纳米研究（英文版）)
年 卷 期：2024年第17卷第5期
页 面：4244-4258页
核心收录：
学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 0836[工学-生物工程] 0702[理学-物理学]
基 金：supported by Key Research Program of Frontier Sciences of CAS(No.QYKJZD-SSW-SLH02)
主 题：micro/nano hybrid materials patterning fabrication techniques extracellular matrix substrate-cell interaction biomedical engineering
摘 要：With the advent of tissue engineering and biomedicine,the creation of extracellular matrix(ECM)biomaterials for in vitro applications has become a prominent and promising *** ECM materials provide physical,biochemical,and mechanical properties that guide cellular behaviors,such as proliferation,differentiation,migration,and *** micro-and nano-patterned materials have a unique surface topology and low energy replication process that directly affect cellular biological behaviors at the interface,the fabrication of micro-nano pattern biomaterials and the regulation of surface physical and chemical properties are of great significance in the fields of cell regulation,tissue engineering,and regenerative ***,we provide a comprehensive review of the progress in the fabrication and application of patterned materials based on the coupling of mechanical action at the micro-and nano-meter scale,including photolithography,micro-contact printing,electron beam lithography,electrospinning,and 3D printing ***,a summary of the fabrication process,underlying principles,as well as the advantages and disadvantages of various technologies are *** also discuss the influence of material properties on the fabrication of micro-and nano-patterns.
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