Epidemiology and characteristics of identified early mpox cases in Guangdong Province,China:Implications for prevention and control

作     者：Yinan Zong Yuwei Yang Dongfeng Kong Jianxiong Xu Zimian Liang Fengxiang Shi Jianhua Huang Min Kang Haojie Zhong Wenjia Liang Yan Li 

作者机构：Public Health Emergency Preparedness and Response DivisionGuangdong Provincial Center for Disease Control and PreventionGuangzhou 511430China Institute for Infectious Disease Control and PreventionGuangdong Provincial Center for Disease Control and PreventionGuangzhou 511430China Institute for Infectious Disease Control and PreventionShenzhen Center for Disease Control and PreventionShenzhen 518055China Deparment of Public Health Emergency Preparednes and ResponseGuangzhou Center for Disease Control and PreventionGuangzhou 510440China Foshan Center for Disease Control and PreventionFoshan 528000China Guangdong Provincial Center for Disease Control and PreventionGuangzhou 511430China 

出 版 物：《Biosafety and Health》 (生物安全与健康（英文）)

年 卷 期：2023年第5卷第6期

页      面：321-325页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：supported by the Key-Area Research and Development Program of Guangdong Province 

主　　题：Mpox Monkeypox virus Epidemiology MSM 

摘      要：In June 2023,the 2022 global mpox(monkeypox)outbreak began to affect Guangdong Province,one of the first regions in China s Mainland to report mpox *** July 10,2023,93 mpox cases had been reported in Guangdong *** study describes the epidemiological characteristics of these patients by collecting and analyzing data on demographics,sexual behavior,medical history,travel history,clinical symptoms,and diagnostic pathways and *** 93 mpox cases were all men aged 20-48 years,95.70%were men who have sex with men(MSM),and 48.39%were HIV-positive.A few cases were married(to women)or living with *** rash was present in almost all cases(98.91%),with the most common sites being the genital and perianal areas(70.33%).Intimate sexual contact was suspected to be the main route of infection,with a median incubation period of 8.5 days(IQR 5.0–11.8).The number of cases increased rapidly,and most patients had no history of international travel,suggesting sustained community transmission within the MSM population in Guangdong *** addition,93.55%of cases were detected by medical institutions,and more than half of these patients had two or more hospital visits before being diagnosed as an mpox case,indicating that clinicians need further training to increase their sensitivity to *** interventions should prioritize MSM while remaining vigilant for transmission to other populations,such as women and children.