Malignant peripheral nerve sheath tumor with hemophilic syndrome and bone marrow fibrosis:A rare case report

作     者：Hui Li Li Wang Ying-Hong Wu Gang Chen Hong-Xia Li Li-Fen Fan Min Gu Cai-Hong Jiang 

作者机构：Department of Medical OncologyOrdos Central HospitalOrdos 017000Inner Mongolia Autonomous RegionChina Department of PathologyOrdos Central HospitalOrdos 017000Inner Mongolia Autonomous RegionChina Department of NeurologyBaogang HospitalBaotou 014010Inner Mongolia Autonomous Region 014010China Department of PharmacyOrdos Central HospitalOrdos 017000Inner Mongolia Autonomous RegionChina Department of OrthopedicsOrdos Central HospitalOrdos 017000Inner Mongolia Autonomous RegionChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2023年第11卷第31期

页      面：7673-7679页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Malignant peripheral nerve sheath tumor Hemophilic syndrome Bone marrow fibrosis Case report 

摘      要：BACKGROUND Malignant schwannoma is a rare tumor in the peripheral nervous system,accounting for approximately 5%to 10%of systemic soft tissue ***,malignant schwannoma occurring in the broad ligament of the uterus with hemophilic syndrome and bone marrow fibrosis is extremely rare in clinical ***,we report the first case of an patient diagnosed with malignant peripheral nerve sheath tumor(MPNST)of the broad ligament of the uterus with hemophilic syndrome and bone marrow fibrosis,and share our reference clinical diagnosis and treatment *** SUMMARY A patient was diagnosed with MPNST of the uterus harboring hemophilic syndrome and bone marrow *** received combination,and repeated imaging revealed further encountered rare complications(hemophilia syndrome and bone marrow fibrosis)after two cycles of ***,combined treatment with pazopanib,gemcitabine,and dacarbazine was ***,the patient succumbed to death at hospital after two *** This report firstly provided reference clinical practice for a patient with MPNST of the uterus harboring hemophilic syndrome and bone marrow *** case raises a reminder about the tolerance and safety of combination therapy,especially in young women.