Intracranial infection accompanied sweet’s syndrome in a patient with anti-interferon-γautoantibodies:A case report
作者机构：General Internal MedicineAffiliated Cancer Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Intensive Care UnitAffiliated Cancer Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2023年第11卷第32期
页 面：7926-7934页
核心收录：
学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100212[医学-眼科学] 10[医学]
基 金：2020 Guangxi University Young and Middle aged Teachers'Basic Research Ability Improvement Project No.2020KY03032
主 题：Adult-onset immunodeficiency syndrome Anti-interferon-gamma autoantibodies Intracranial infection Sweet disease Case report
摘 要：BACKGROUND Several reports of adult-onset immunodeficiency syndrome have been associated with anti-interferon-gamma(IFN-γ)autoantibodies(AIGAs).However,it is rare to find AIGAs with intracranial *** SUMMARY In this case study,we report a case of an AIGAs with intracranial infection and hand rashes considered Sweet’s *** patient presented to our hospital with a persistent cough,a fever that had been going on for 6 mo,and a rash that had been going on for a *** patient started losing consciousness gradually on the fourth day after admission,with neck stiffness and weakened limb *** upper lobe of the left lung had a high-density mass with no atypia and a few inflammatory cells in the *** magnetic resonance imaging and cerebrospinal fluid suggest intracranial *** pathology of the skin damage on the right upper extremity revealed an infectious lesion that was susceptible to Sweet’s *** has an anti-IFN-γautoantibody titer of 1:*** was given empirical anti-non-tuberculous mycobacterial and antifungal *** patient had no fever,obvious cough,headache,or rash on the *** got out of bed and took care of herself following hospitalization and discharge with *** Adults with severe and recurrent infections of several organs should be considered for AIGAs if no other known risk factors *** are susceptible to subsequent intracranial infections and Sweet’s syndrome.
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