Monkeypox virus(MPXV):A Brief account of global spread,epidemiology,virology,clinical features,pathogenesis,and therapeutic interventions
作者机构：Advanced Molecular LabDepartment of MicrobiologyPresident Abdul Hamid Medical CollegeKarimganj 2310Bangladesh COVID-19 Diagnostic LabDepartment of MicrobiologyNoakhali Science and Technology UniversityNoakhali 3814Bangladesh Department of Global Public HealthKarolinska InstitutetSE-17177 StockholmSweden Department of Public HealthNorth South UniversityDhaka 1229Bangladesh Department of Biochemistry and Molecular BiologyFaculty of AgricultureHajee Mohammad Danesh Science and Technology UniversityDinajpur 5200Bangladesh Shandong Vocational Animal Science and Veterinary CollegeWeifang 261061China COVID-19 Research@KTHDepartment of Sustainable DevelopmentEnvironmental Science and EngineeringKTH Royal Institute of TechnologySE-10044 StockholmSweden Key Laboratory of Animal Epidemiology and Zoonoses of Ministry of AgricultureCollege of Veterinary MedicineChina Agricultural UniversityBeijing 100019China Department of MicrobiologyFaculty of Veterinary and Animal ScienceHajee Mohammad Danesh Science and Technology UniversityDinajpur 5200Bangladesh
出 版 物：《Infectious Medicine》 (感染医学（英文）)
年 卷 期：2023年第2卷第4期
页 面：262-272页
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
主 题：Monkeypox(MPX) Monkeypox virus(MPXV) Epidemiology Zoonotic diseases Re-emerging viruses Genomic dissemination Vaccination and Treatment
摘 要：The largest monkeypox virus(MPXV)outbreak of the 21st century occurred in 2022,which caused epidemics in many *** to WHO,physical contact with infected persons,contaminated surfaces,or affected animals might be a source of this virus transmission.A febrile sickness including few symptoms found in MPX *** rash,lesions,fever,headache,fatigue,and muscle aches symptoms were observed commonly for this *** and in vitro,studies have shown that the antiviral medications cidofovir and brincidofovir are effective against *** first-generation vaccinia virus vaccine was developed in 1960,and it helped to protect against MPXV with its side effects.A second-generation vaccination with limitations was launched in ***,the CDC advised vaccinations for risk groups in endemic countries,including positive patients and hospital *** JYNNEOS vaccine,administered in 2 doses,also provides protection from *** article presents concisely the most recent findings regarding epidemiology,genomic transmission,signs and symptoms,pathogenesis,diagnosis,and therapeutic interventions for MPXV,which may be helpful to researchers and *** declared that MPX was no longer a global health emergency due to its declining case rate,and a number of countries have reported new *** research-based investigations must be carried out based on the 2022 outbreak.
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