Prediabetes in children and adolescents:An updated review

作     者：Hak Yung Ng Louis Tsz Wang Chan 

作者机构：Department of Paediatrics and Adolescent MedicineTseung Kwan O HospitalHong KongChina 

出 版 物：《World Journal of Clinical Pediatrics》 (世界临床儿科杂志)

年 卷 期：2023年第12卷第5期

页      面：263-272页

学科分类：1002[医学-临床医学] 100202[医学-儿科学] 10[医学] 

主　　题：Prediabetes Screening Diagnosis Management Obesity Type 2 diabetes mellitus Children 

摘      要：Prediabetes,the precursor of type 2 diabetes mellitus,is an intermediate stage between normal glucose homeostasis and overt *** asymptomatic metabolic state is increasingly prevalent in pediatric population and is very difficult to detect without appropriate *** have shown that a certain proportion of children with prediabetes will develop diabetes in a few *** more alarming is the evidence that youth-onset diabetes has a more aggressive clinical course with progressive beta-cell decline and accelerated endorgan *** its importance,several aspects involving prediabetes in childhood are disputed or *** review presents the latest insights into this challenging entity and outlines a simplified screening approach to aid clinical *** summary,childhood prediabetes is an important clinical condition indicating the need for proper screening and timely intervention.