Arterial spin labeling perfusion MRI applications in drug‑resistant epilepsy and epileptic emergency

作     者：Yingchun Xu Ge Tan Deng Chen Jiao Liu Zixian Zhou Ling Liu Yingchun Xu;Ge Tan;Deng Chen;Jiao Liu;Zixian Zhou;Ling Liu

作者机构：Department NeurologySichuan UniversityWest China HospitalGuo Xue Lane 37Chengdu 610041SichuanPR China 

出 版 物：《Acta Epileptologica》 (癫痫学报（英文）)

年 卷 期：2023年第6卷第3期

页      面：139-147页

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：Science and Technology Department of Sichuan Province, SPDST, (2021YFS0174) Health Commission of Sichuan Province, (20ZD005) 

主　　题：Arterial spin labeling Cerebral blood flow Drug-resistant epilepsy Epileptic emergency Status epilepticus SUDEP 

摘      要：Epilepsy affects all age groups and is one of the most common and disabling neurological disorders ***-resistant epilepsy(DRE),status epilepticus(SE),and sudden unexpected death in epilepsy(SUDEP),which are associated with considerable healthcare costs and mortality,have always been difficult to address and become the focus of clinical *** rapid identification of seizure onset and accurate localization of epileptic foci are crucial for the treatment and prognosis of people with DRE,SE,or ***,most of the conventional neuroimaging techniques for assessing cerebral blood flow of people with epilepsy are restricted by time consumption,limited resolution,and ionizing *** spin labeling(ASL)is a newly powerful non-contrast magnetic resonance imaging technique that enables the quantitative evaluation of brain perfusion,characterized by its unique advantages of reproducibility and easy *** studies have demonstrated the potential advantages of ASL for the diagnosis and evaluation of ***,in this review,we discussed the complementary value of ASL in evaluating and characterizing the basic substrates underlying refractory epilepsy and epileptic emergencies.