Advances in Phytochemistry and Modern Pharmacology of Saposhnikovia Divaricata(Turcz.)Schischk

作     者：GAO Jun-wen ZHAN Yang WANG Yun-he ZHAO Shu-jie HAN Zhong-ming GAO Jun-wen;ZHAN Yang;WANG Yun-he;ZHAO Shu-jie;HAN Zhong-ming

作者机构：College of Resources and EnvironmentJilin Agricultural UniversityChangchun(130118)China Information CenterJilin Agricultural UniversityChangchun(130118)China College of Chinese Medicinal MaterialsJilin Agricultural UniversityChangchun(130118)China 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志（英文版）)

年 卷 期：2023年第29卷第11期

页      面：1033-1044页

核心收录：

学科分类：1006[医学-中西医结合] 1002[医学-临床医学] 10[医学] 100602[医学-中西医结合临床] 

基　　金：Supported by Jilin Scientific and Technology Development Program(No.20210204011YY)。 

主　　题：coumarin synergistic priori 

摘      要：Saposhnikovia divaricata(Turcz.)Schischk(S.divaricata,Fangfeng)is a herb in the Apiaceae family,and its root has been used since the Western Han Dynasty(202 B.C.).Chromones and coumarins are the pharmacologically active substances in S.divaricata.Modern phytochemical and pharmacological studies have demonstrated their antipyretic,analgesic,anti-inflammatory,antioxidant,anti-tumor,and anticoagulant activities.Technological and analytical strategy theory advancements have yielded novel results;however,most investigations have been limited to the main active substances—chromones and coumarins.Hence,we reviewed studies related to the chemical composition and pharmacological activity of S.divaricata,analyzed the developing trends and challenges,and proposed that research should focus on components’synergistic effects.We also suggested that,the structure-effect relationship should be prioritized in advanced research.