Engineered microneedles arrays for wound healing

作     者：Shun Yao Yuan Luo Yongan Wang 

作者机构：State Key Laboratory of Toxicology and Medical CountermeasuresBeijing Institute of Pharmacology and ToxicologyBeijing 100850China 

出 版 物：《Engineered Regeneration》 (再生工程（英文）)

年 卷 期：2022年第3卷第3期

页      面：232-240页

核心收录：

学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：supported by the Special Fund for Military Medical Science(AWS17J009). 

主　　题：Engineered design Microneedles arrays Wound healing 

摘      要：Wound healing is the regenerative process of original skin structure after destructing by different damage sources.Due to their transdermal delivery capability and high specific surface area,microneedles arrays(MAs)have been recognized as encouraging biomaterials for wound healing.In this review,we have outlined the engineered MAs used for tissue regeneration and wound healing.Engineered MAs were first classified by design methodologies such as bionic design,intelligent-responsive design,actively-triggered design,matrix materials innovation,and composite smart design.Then,the MAs were divided into two categories based on the different loading substances:drug-loaded MAs and living component-loaded MAs.Finally,we have summed up the important elements of the preceding discussions and forecasted their future evolution.