Synthesis of tetraarylmethanes:1897–2022

作     者：Lai Chen Jingqian Huo Jinlin Zhang Judith N.Currano Haixing Guan Patrick J.Walsh Jianyou Mao 

作者机构：College of Plant ProtectionHebei Agricultural UniversityBaoding 071000China Department of ChemistryUniversity of PennsylvaniaPennsylvania 19104-6323United States Experimental CenterShandong Provincial Key Laboratory of Traditional Chinese Medicine for Basic ResearchKey Laboratory of Traditional Chinese Medicine Classical TheoryMinistry of EducationShandong University of Traditional Chinese MedicineJinan 250355China Technical Institute of Fluorochemistry(TIF)State Key Laboratory of Materials Oriented Chemical Engineering(MCE)School of Chemistry and Molecular EngineeringNanjing Tech UniversityNanjing 211816China 

出 版 物：《Green Synthesis and Catalysis》 (绿色合成与催化（英文）)

年 卷 期：2023年第4卷第4期

页      面：273-292页

学科分类：1002[医学-临床医学] 0703[理学-化学] 100214[医学-肿瘤学] 10[医学] 

基　　金：The authors acknowledged the National Natural Science Foundation of China(Nos.32272572,32272573 and 32001927) the Natural Science Foundation of Hebei Province,China(No.22326503D) JM acknowledged the National Natural Science Foundation of China(No.22071107) Natural Science Foundation of Jiangsu Province,China(No.BK20211588) PJW acknowledged the US National Science foundation(No.CHE-2154593) 

主　　题：Tetraarylmethane Tetraphenylmethane Cross-coupling Palladium Radicals Fridel-crafts Quaternary carbons 

摘      要：Tetraarylmethanes(TAMs)contain a carbon atom bound to four aryl *** have found diverse applications in chemistry,materials science,chemical biology and medicinal chemistry because of their unique 3-dimensional *** a reflection of the high demand for TAMs,over 32,000 unique TAMs have been *** distinct structures of TAMs and the crowded nature of the central carbon atom require different strategies for their *** we present the first review on the synthesis of TAMs,from classical approaches to modern methods,including enantioselective syntheses of *** provide a critical evaluation of methods and highlight important directions for future research into the synthesis of this aesthetically pleasing and very useful class of spherical structures.