The Principles of Insulin Management of Type 2 Diabetes Mellitus
The Principles of Insulin Management of Type 2 Diabetes Mellitus作者机构:Internal Medicine Division Port Moresby General Hospital Port Moresby Papua New Guinea Department of Geriatric Eastbourne District General Hospital East Sussex NHS Trust Eastbourne UK
出 版 物:《Journal of Diabetes Mellitus》 (糖尿病(英文))
年 卷 期:2023年第13卷第4期
页 面:284-299页
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:Insulin Type 2 Diabetes Principles of Insulin Therapy
摘 要:Insulin therapy is an integral part of the pharmacological management of Type 2 diabetes mellitus. Guidelines recommended insulin therapy for those patients with suboptimal glycaemic control despite optimal medical treatments. Studies show that insulin therapy with the human and regular insulins improve glycaemic control, reduce the chronic complications, and inevitably improve patient’s quality of life. The new analogue insulin has a better safety profile and efficacies, and has been shown to achieve better outcomes and patient’s acceptability compared with the human and regular insulins. The diabetic guidelines also recommend the intensity of insulin therapy in a personalised glycaemic control strategy based on the patient’s profiles and their preferences. However, the guidelines do not recommend any standardised approach to the principles of insulin initiation, titration, and monitoring. This review summarises the essential principles of insulin initiation, titration, and monitoring in Type 2 diabetes mellitus.