Efficacy and safety of deep sclerectomy with uveoscleral implant plus collagen matrix implant overcoming the superficial scleral flap in glaucoma surgery

作     者：Jéssica Botella-García Marta Balboa Pau Romera-Romero Theo Stijnen Adrián Sánchez-Fortún Karl Mercieca Jordi Loscos-Arenas 

作者机构：Department of OphthalmologyHospital Germans Trias i PujolBadalona 08916Spain International University of Catalonia(UIC)Barcelona 08017Spain Department of SurgeryBarcelona Autonomous University(UAB)Barcelona 08035Spain Department of Biomedical Data SciencesLeiden University Medical CenterLeiden 2333The Netherlands University Hospitals Bonn Eye ClinicBonn53127Germany Germans Trias i Pujol Research Institute(IGTP)Badalona 08916Spain 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2023年第16卷第11期

页      面：1806-1813页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：deep sclerectomy glaucoma surgery uveoscleral implant 

摘      要：AIM:To assess the efficacy and safety of non-penetrating deep sclerectomy(NPDS)with uveoscleral implant plus subconjunctival and intrascleral collagen matrix overcoming the superficial scleral flap lips(modified deep sclerectomy technique,DS)and minimal use of mitomycin C in glaucoma ***:A retrospective review of 47 consecutive glaucoma patients who underwent NPDS with DS between January 2017 and May ***-corrected visual acuity,intraocular pressure(IOP),post-operative need for glaucoma medications,visual field mean deviation(MD),re-interventions,needling revisions and laser goniopuncture were *** success was defined as IOP≤18 mm Hg without topical *** success was defined as the same criteria but with the addition of any antihypertensive *** over 18 mm Hg on two consecutive followup visits was considered as a ***:Fifty-two eyes of 47 patients were *** preoperative IOP was 25.37±6.47 mm Hg,and decreased to 15.04±4.73 at 12mo and 12.21±4.1 at 24mo(all P0.0001).Requirement for topical medications dropped from a mean of 3.06±0.25 per patient to 0.51±0.99 and 1.11±1.23 respectively after 12 and 24mo(all P0.0001).No medications were required in 45.5%of patients after *** and absolute success rate at 24mo were 85.5%±5%and 48.5%±7.4%,***:DS is a safe and effective nonpenetrating glaucoma surgery *** aims to retain the patency of all pathways created for aqueous humor drainage:the intrascleral bleb,the supraciliary space and the open communication between intrascleral and subconjunctival compartments.