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Real-Time Monitoring of Dynamic Chemical Processes in Microbial Metabolism with Optical Sensors

作     者:Na Chen Di Cheng Tianpei He Quan Yuan Na Chen;Di Cheng;Tianpei He;Quan Yuan

作者机构:Institute of Molecular MedicineRenmin Hospital of Wuhan UniversityCollge of Chemistry and Molecular SciencesWuhan UniversityWuhanHubei 430072China Molecular Science and Biomedicine Laboratory(MBL)State Key Laboratory of Chemo/Biosensing and ChemometricsCollege of Chemistry and Chemical EngineeringHunan UniversityChangshaHunan 410082China 

出 版 物:《Chinese Journal of Chemistry》 (中国化学(英文版))

年 卷 期:2023年第41卷第15期

页      面:1836-1840页

核心收录:

学科分类:0710[理学-生物学] 07[理学] 0703[理学-化学] 071005[理学-微生物学] 

基  金:The National Natural Science Foundation of China(21925401)is acknowledged for research funding。 

主  题:Real-time Microbial metabolism Dynamic Monitoring Optical biosensor 

摘      要:Monitoring microbial metabolism is vital for revealing the mechanism of disease related to microbial metabolism and providing guidance for biomanufacturing processes optimization.However,it remains a grand challenge to offer real-time insights into microbial metabolism owing to the complex and dynamic process.In this paper,the recent advances and prospects of optical biosensors including the organic,genetic coding and inorganic optical biosensors are briefly described for real-time monitoring of dynamic microbial metabolism.This paper points out that challenges remain in microbial heterogeneity.We believe that this work will inspire the application of developing new methods for single cell real-time analysis.

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