Functionalization of C,C-palladacycles:application in the synthesis of functional molecules

作     者：Dong Wei Guo-Qiang Lin 

作者机构：State Key Laboratory of Systems Medicine for CancerShanghai Cancer InstituteRen Ji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Key Laboratory of Synthetic Chemistry of Natural SubstancesShanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China 

出 版 物：《中国科学:化学英文版》 (SCIENCE CHINA Chemistry)

年 卷 期：2023年第66卷第10期

页      面：2721-2733页

核心收录：

学科分类：081705[工学-工业催化] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 

基　　金：This work was supported by the National Natural Science Foundation of China(22101296) the State Key Laboratory of Systems Medicine for Cancer(SB23-09,KF2130-93). 

主　　题：C,C-palladacycles functionalization synthetic application 

摘      要：Significant advancements have been achieved in the field of C,C-palladacycles functionalization in recent decades,which have greatly contributed to the synthesis of intricate drug molecules,natural products,innovative materials,and chiral ligands.Additionally,these advancements have led to the establishment of highly efficient and atom-economic synthetic processes.Based on the differences in the C–Pd bonds,C,C-palladacycles can be further classified into several main types:C(aryl),C(alkyl)-,C(aryl),C(aryl)-,C(aryl),C(vinyl)-,and C(alkyl),C(carbonyl)-palladacycles.This minireview will highlight the recent advances in the synthesis of functional molecules through the functionalization of different C,C-palladacycles,and we hope this survey will inspire future strategic developments for C,C-palladacycle catalysts and their synthetic application.