Emulation of Brain Metabolic Activities Based on a Dynamically Controllable Optical Phantom

作     者：Yuxiang Lin Cheng Chen Zhouchen Ma Nabil Sabor Yanyan Wei Tianhong Zhang Mohamad Sawan Guoxing Wang Jian Zhao 

作者机构：Department of Micro-Nano ElectronicsShanghai Jiao Tong UniversityShanghaiChina Electrical Engineering DepartmentFaculty of EngineeringAssiut UniversityAssiutEgypt Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina CenBRAIN NeurotechSchool of EngineeringWestlake UniversityHangzhouChina 

出 版 物：《Cyborg and Bionic Systems》 (类生命系统（英文）)

年 卷 期：2023年第4卷第1期

页      面：84-92页

核心收录：

学科分类：070207[理学-光学] 07[理学] 08[工学] 0803[工学-光学工程] 0702[理学-物理学] 

基　　金：supported by the National Key Research and Development Program of China under Grant No.STI2030-Major Projects 2022ZD0208500 

主　　题：dynamic powder titanium 

摘      要：This paper presents a dynamic optical phantom for the simulation of metabolic activities in the brain,and a linear equivalent model is built for control voltage versus substance concentration.A solid-solid dynamic optical phantom is realized by using liquid crystal film as a voltage-controlled light intensity regulator on the surface of basic phantom,which uses epoxy resin as matrix material and nanometer carbon powder and titanium dioxide powder as absorption and scattering dopants,*** dynamic phantom could mimic near-infrared spectrum(NIRS)signals with sampling rate up to 10 Hz,and the maximum simulation errors for oxy-hemoglobin and deoxy-hemoglobin concentrations varying in the range of 1μmol/l are 7.0%and 17.9%,*** with similar solid biomimetic phantoms,the adjustable mimic substance concentration range is extended by an order of magnitude,which meets the simulation requirements of most brain NIRS signals.