New insights into the role of the immune inhibitory receptor VSTM1 in autoimmune disease

作     者：Najun Miaol Jing Wang 

作者机构：Center for Immune-related Diseases at Shanghai Institute of ImmunologyRujin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina 

出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)

年 卷 期：2024年第21卷第1期

页      面：95-96页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(82371760)to JW 

主　　题：immunity immune autoimmune 

摘      要：Immune inhibitory receptors(IRs)are germline-encoded transmembrane receptors that function as negative regulators of immune cells and dampen the cellular response to keep the immune system in balance^([1]).There are more than 300 potential immune IRs encoded in the human genome^([2]).The most studied IRs in cancer immunity are programmed cell death protein 1,cytotoxic T lymphocyte protein 4 in T cells,and killer cell Ig-like IRs on NK cells^([3]).