Systemic treatment for advanced pancreatic cancer
作者机构：Department of Clinical Tropical MedicineMahidol UniversityRachatawee 10400BangkokThailand Department of MedicineSrinakharinwirot UniversityWattana 10110BangkokThailand
出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志(英文版)(电子版))
年 卷 期：2023年第15卷第10期
页 面：1691-1705页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Systemic treatment Advanced pancreatic cancer Personalized medicine Biomarkers Chemotherapy Targeted therapy Immunotherapy
摘 要：Pancreatic cancer is a deadly disease with an extremely poor 5-year survival rate due to treatment resistance and late-stage *** numerous years of research and pharmaceutical development,these figures have not *** options for advanced pancreatic cancer are still *** illness is typically detected at a late stage,making curative surgical resection *** is the most commonly utilized technique for treating advanced pancreatic cancer but has poor *** therapy and immunotherapy have made significant progress in many other cancer types and have been proven to have extremely promising possibilities;these therapies also hold promise for pancreatic *** is an urgent need for research into targeted treatment,immunotherapy,and cancer *** this review,we emphasize the founda-tional findings that have fueled the therapeutic strategy for advanced pancreatic *** also address current advancements in targeted therapy,immuno-therapy,and cancer vaccines,all of which continue to improve the clinical outcome of advanced pancreatic *** believe that clinical translation of these novel treatments will improve the low survival rate of this deadly disease.
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