Whole-genome Duplication Reshaped Adaptive Evolution in A Relict Plant Species,Cyclocarya paliurus

作     者：Yinquan Qu Xulan Shang Ziyan Zeng Yanhao Yu Guoliang Bian Wenling Wang Li Liu Li Tian Shengcheng Zhang Qian Wang Dejin Xie Xuequn Chen Zhenyang Liao Yibin Wang Jian Qin Wanxia Yang Caowen Sun Xiangxiang Fu Xingtan Zhang Shengzuo Fang 

作者机构：Nanjing Forestry UniversityCo-Innovation Center for Sustainable Forestry in Southern ChinaNanjing 210037China Shenzhen BranchGuangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China Center for Genomics and BiotechnologyFujian Provincial Key Laboratory of Haixia Applied Plant Systems BiologyKey Laboratory of GeneticsBreeding and Multiple Utilization of CropsMinistry of EducationFujian Agriculture and Forestry UniversityFuzhou 350002China 

出 版 物：《Genomics, Proteomics & Bioinformatics》 (基因组蛋白质组与生物信息学报（英文版）)

年 卷 期：2023年第21卷第3期

页      面：455-469页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 0711[理学-系统科学] 07[理学] 08[工学] 

基　　金：funded by the National Natural Science Foundation of China(Grant Nos.31971642,32271859,32071750,31470637,and 32222019) This work was also supported by the Key R&D Program of Jiangsu Province(Grant No.BE2019388) the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD),China 

主　　题：Cyclocarya paliurus Genomics Whole-genome duplication Triterpenoid Resequencing 

摘      要：Cyclocarya paliurus is a relict plant species that survived the last glacial period and shows a population expansion *** leaves have been traditionally used to treat obesity and diabetes with the well-known active ingredient cyclocaric acid ***,we presented three *** genomes from two diploids with different flower morphs and one haplotype-resolved tetraploid *** genomic analysis revealed two rounds of recent whole-genome duplication events and identified 691 genes with dosage effects that likely contribute to adaptive evolution through enhanced photosynthesis and increased accumulation of *** analysis of 45 *** individuals uncovered two bottlenecks,consistent with the known events of environmental changes,and many selectively swept genes involved in critical biological functions,including plant defense and secondary metabolite *** also proposed the biosynthesis pathway of cyclocaric acid B based on multi-omics data and identified key genes,in particular gibberellinrelated genes,associated with the heterodichogamy in *** *** study sheds light on evolutionary history of *** and provides genomic resources to study the medicinal herbs.